Expert knowledge on fertility, preconception care, and life planning shared by Dr. Takuma Sato.
Does CoQ10 improve egg quality? A meta-analysis reports higher clinical pregnancy rates in women with diminished ovarian reserve, but no improvement in live birth has been shown. Here is what has and has not been established, with sample sizes and study types.
Repeated cycles do raise success rates. But after 40, six retrieval cycles still leave a conservative cumulative live birth estimate of 14.7%. Here are the numbers, and how to think about when to stop.
A normal semen analysis tells you nothing about DNA damage. But professional societies do not recommend testing everyone. Here is what is established, when testing is considered, and what supplements do and do not do.
Pooled cohort studies of 3,711 women undergoing IVF report higher live birth rates among those with sufficient vitamin D. That is an association — it is not evidence that taking a supplement improves outcomes.
Periodontal disease is known to affect overall health, and research suggests it may also be linked to fertility and pregnancy outcomes. Discover how oral care could relate to your future pregnancy journey.
Age-related difficulty conceiving is usually attributed to egg quality, but recent research suggests the receptivity of the uterus also matters. I explain what that means for implantation.
In the journey of trying to conceive (TTC), social media can be a valuable resource but also a source of mental health challenges. As a specialist, I'll discuss its pros, cons, and tips to protect your well-being.
Seed cycling is a popular trend in the TTC community for balancing hormones and boosting fertility. But what does science say? An OB/GYN explains the current evidence.
For women on their TTC journey, exercise offers significant benefits for overall health. However, questions often arise about how exercise intensity affects reproductive function. This article explores the potential impacts of high-intensity vs. moderate activity on female fertility from an expert perspective.
As a fertility specialist, I explain what the latest research does and does not tell us about how the gut microbiome may influence reproductive function.
Fertility treatment can place a heavy load on mind and body. A fertility specialist explains how mindfulness may help ease that stress, with concrete techniques you can practice.
Exploring the current research on the potential link between air pollution and reproductive health. Understand environmental factors to consider for future family planning.
What tests are actually useful for diagnosing endometriosis? From non-invasive tests to laparoscopy, here is what each one offers and how the position of laparoscopy has shifted.
PGT-A (Preimplantation Genetic Testing for Aneuploidy) is an advanced option in IVF treatment, but its efficacy varies depending on age group and individual circumstances. This article, from the perspective of a fertility specialist, objectively discusses the scientific basis, expected benefits, and limitations of PGT-A.
An evidence-based look at how diet may influence sperm quality in men who are trying to conceive, and what the research can and cannot yet tell us.
Why does good-quality sleep matter when you are trying to conceive? As a fertility specialist, I explain what current findings suggest about sleep quality, ovulation, and egg quality.
When planning for pregnancy, folate intake is crucial. However, the distinction between "activated folate" (methylfolate) and "folic acid" (pteroylmonoglutamic acid) can be confusing amidst the vast amount of information available. From the perspective of a fertility specialist, this article will explore the latest evidence on methylfolate and folic acid, and their connection to MTHFR gene mutations.
A low proportion of Lactobacillus has been reported alongside implantation failure. But an association being reported and testing-and-treating changing the outcome are two different things — and the antibiotic data shows the gap clearly.
A 2024 meta-analysis of 14 studies and 1,632 patients found no significant change in AMH. Antral follicle count and oocytes retrieved rose slightly — by about one oocyte. Pregnancy and live birth were not reported.
A 2024 systematic review of 30 studies and 27,901 people found no effect on overall fertility at everyday exposure levels — but moderate associations with sperm motility and DNA integrity. A Singapore cohort found the opposite. The picture is patchy.
Explore the latest evidence on progesterone supplementation for miscarriage prevention in women with a history of recurrent miscarriage. Understand its potential, limitations, and scientific basis.
Ovulation Predictor Kits (OPKs) and Basal Body Temperature (BBT) are two widely used methods for women trying to conceive (TTC) to identify ovulation. From a fertility specialist's perspective, we'll explain how each works, their pros and cons, and the optimal way to use them to increase your chances of conception.
A meta-analysis of 20 randomised trials found no difference in live birth for non-male-factor infertility — and a significantly higher clinical pregnancy rate with conventional IVF. But conventional IVF carries a risk of total fertilisation failure. Both sides, laid out.
A fertility specialist explains, calmly and on the basis of current evidence, how a man's age may influence sperm quality, the chance of pregnancy and the health of the child.
As a fertility specialist, I review what the current evidence says about how shift work may affect female reproductive function, and what women trying to conceive should keep in mind.
For women with Polycystic Ovary Syndrome (PCOS), how does myo-inositol impact ovulation and pregnancy rates? We explore the possibilities based on the latest evidence.
Explore the complex link between autoimmune conditions and infertility, understanding how immune system dysregulation may impact reproductive health.
An objective look at how sperm morphology impacts conception and IVF. Teratozoospermia doesn't always mean infertility.
A fertility specialist reviews what current evidence does and does not tell us about celiac disease, infertility and pregnancy outcomes.
It's natural to feel anxious when your hCG levels are lower than expected in early pregnancy. However, a single low reading doesn't automatically mean miscarriage. A specialist explains the truth about hCG levels and reasons to maintain hope.
Zinc is genuinely involved in sperm formation. But in a randomised trial of 2,370 men, zinc plus folic acid changed neither live birth (34% vs 35%) nor any semen parameter — and DNA fragmentation rose slightly.
Many individuals on their TTC journey wonder about caffeine intake. Based on the latest evidence, we explore the link between caffeine and fertility, and what a safe daily amount looks like, from an OB/GYN's perspective.
Feeling anxious when your doctor suggests "watchful waiting"? Learn when it might be appropriate to request proactive fertility testing and how to advocate for yourself.
Do you ever feel hesitant to ask questions during your fertility appointments? Strong communication with your doctor is key to successful treatment. This article provides a concrete list of questions to help alleviate your concerns and make informed treatment choices.
For those living in rural areas facing challenges accessing fertility clinics, telemedicine and remote monitoring are opening new doors. Learn how these technologies can support your unique TTC journey.
A fertility specialist objectively discusses the cost-effectiveness of advanced reproductive technologies like SEET and IMSI. Get accurate information to understand how these treatments might fit into your future family planning.
The fertility journey can be long, and deciding when to stop treatment is rarely easy. This article explores concrete steps and emotional support for making this challenging decision.
Is timed intercourse making your sex life feel like a burden during your TTC journey? Feeling pressured is a valid emotion. A fertility specialist offers tips for couples to navigate intimacy while trying to conceive.
Are innocent questions like "When are you having kids?" from in-laws or relatives causing significant stress during your TTC journey? A fertility specialist explains how to alleviate this psychological burden and set healthy boundaries.
For women undergoing fertility treatment, balancing work and appointments can be a significant challenge. We discuss the stress of hiding your journey and the potential benefits of disclosing it to your employer, from the perspective of an OB/GYN specialist.
Having complicated feelings about a friend's pregnancy announcement is natural. A fertility specialist explains psychological approaches for validating those feelings while protecting your heart.
The gap in how you and your partner feel about trying to conceive is common. A fertility specialist shares practical communication techniques for deeper mutual understanding.
The phrase 'Just relax and you'll get pregnant' is often a hurtful piece of advice for those struggling with infertility. This article provides a scientific, calm perspective on the relationship between infertility and stress.
Many people wonder, "Is this implantation bleeding?" Differentiating between implantation bleeding and a period can be challenging. This article, from an OB-GYN specialist’s perspective, explains the mechanism of implantation bleeding, how to distinguish it from a period, and addresses the debate surrounding whether it’s a "myth," incorporating the latest insights.
Fertility apps offer convenience for ovulation tracking, but many wonder about their accuracy and why predictions differ. This article, written by a fertility specialist, explains how these apps work, reasons for discrepancies, and tips to improve prediction accuracy.
If you've been told you have high FSH and feel concerned, this article explains the difference between FSH and AMH, and explores the possibility of pregnancy even with elevated FSH levels.
ASRM stated in a 2021 committee opinion that luteal phase deficiency has not been proven to be an independent cause of infertility or recurrent pregnancy loss. Here is where this concept actually stands.
If your menstrual cycles are long and irregular, ranging from 32 to 60 days, it's natural to feel concerned about conception. Learn how to predict ovulation and effectively time intercourse with expert guidance.
AMH and AFC are crucial indicators of ovarian reserve, but sometimes their values don't align. Why does this discordance occur? This article explains the reasons and how to make a more informed decision.
Using an Ovulation Predictor Kit (OPK) and consistently not seeing a positive result can be distressing. While Polycystic Ovary Syndrome (PCOS) is a common concern, there are several other reasons why your OPK might not be turning positive. This article, from the perspective of an OB/GYN specialist, explains the main causes and potential strategies.
When is the optimal timing for Intrauterine Insemination (IUI) – before or after ovulation? We delve into the latest meta-analysis to provide an expert perspective on its effectiveness.
If your embryos don't develop to the blastocyst stage, early embryo transfer can be a valid alternative. A specialist explains why, its pros and cons, and when to consider this option.
Two consecutive single transfers versus one double transfer: cumulative live birth 48.24% vs 48.91%, cumulative multiple pregnancy 0.87% vs 17.72%. Almost the same chance of a baby, about twenty times the difference in twins.
If you've experienced a lower-than-expected egg retrieval, you're not alone in wondering if a change in stimulation protocol is necessary for your next cycle. This article delves into the definition of a poor responder and the scientific basis for protocol modifications from a specialist's perspective.
Five signs worth weighing calmly when you have doubts about your current fertility clinic, and what to do next.
Navigating the decision of how many IUI cycles to undergo before considering IVF is challenging. This article explores the latest data and emphasizes validating your emotions throughout the fertility journey.
A diagnosis of missed miscarriage can be emotionally overwhelming. Learn when to consider a second opinion and what criteria to use.
Many women experience anxiety in early pregnancy. An OB/GYN specialist explains practical coping strategies to ease worries between ultrasound appointments.
Seeing a gestational sac but no heartbeat in early pregnancy can be incredibly worrying. This article, written by an OB/GYN specialist, explains the appropriate timing for heartbeat confirmation and medical criteria to help you wait with less anxiety.
Miscarriage is never "your fault." We debunk common myths about exercise, stress, and coffee causing miscarriage, based on the latest scientific evidence.
The common advice to 'wait 3 months' after a miscarriage before trying to conceive again is being challenged by new evidence. We provide information based on the latest research to help you navigate your TTC journey.
For those who've experienced a chemical pregnancy. A message from a specialist addressing the impact on future pregnancies, recurrence rates, and validating your feelings.
It's common for expectant mothers to worry about miscarriage if their morning sickness symptoms suddenly lessen or disappear. However, research indicates that the intensity and frequency of morning sickness vary greatly among individuals and often fluctuate.
Bleeding in early pregnancy is something many pregnant people experience, yet it understandably causes worry. A fertility specialist explains how to tell a warning sign from a benign one.
Many foods deeply embedded in modern diets are ultra-processed. A fertility specialist discusses recent findings suggesting their potential impact on hormonal balance and reproductive function for women trying to conceive.
Is the idea that certain sexual positions increase pregnancy chances a myth? We explore the scientific truths about intercourse timing and positions in fertility planning.
Postpartum exercise and pelvic floor muscle training (PFMT) are crucial for preventing and improving urinary incontinence and mental health issues. This article outlines evidence-based postpartum care, guided by the latest Canadian recommendations.
Can "fertility detox" diets and supplements truly create a body more conducive to pregnancy? An OB/GYN expert analyzes the scientific basis behind these claims.
Natural and programmed frozen embryo transfer give similar live birth rates. What high-certainty evidence does show is less pregnancy loss when the cycle involves ovulation. The difference in hypertensive disorders has not been established. Here is what is known and what is not.
What has been shown about endocrine disrupting chemicals and microplastics, and what has not — separated clearly, along with practical ways to reduce exposure.
"Gluten-free" and "dairy-free" diets are often discussed in the context of trying to conceive (TTC). But do these restrictions truly help with fertility? This article explains the scientific evidence behind infertility and dietary therapies from the perspective of an OB/GYN specialist.
In a trial of 848 women undergoing IVF, acupuncture produced no difference in live birth compared with sham acupuncture. Why results change depending on what acupuncture is compared against.
Time-lapse incubation allows embryos to be watched continuously. In a double-blind randomised trial of 1,575 patients, live birth rates were 33.7% with time-lapse and 33.0% with standard care. Here is what the trials show, and what they do not.
As an OB/GYN specialist, I'll explain the challenges men with low testosterone face in fertility, how testosterone replacement therapy impacts sperm production, and current treatment strategies.
For treatments starting on or after 1 April 2026, out-of-pocket costs for insurance-covered IVF and ICSI are now eligible for Tokyo's subsidy. Applications open on 1 October 2026. Here is how the ¥150,000 cap works and what the deadline means, based on official sources.
In a double-blind randomised trial of 767 patients, timing transfer by endometrial receptivity testing did not raise live birth rates (58.5% vs 61.9%). Here are the numbers, and the parts that are still unanswered.
Do you have vague anxieties about future pregnancy, childbirth, or career plans? Preconception care is a health investment you can make now, even if you're not planning pregnancy yet, to expand your future options. A specialist explains concrete steps you can take starting today.
Address the critical importance of mental well-being before, during, and after pregnancy. Understand common mental health challenges like anxiety and depression, and learn about available support systems and resources.
Explore the cutting-edge AI research aiming to improve IVF success rates. We delve into the potential of AI to predict embryo quality and pregnancy outcomes, based on robust evidence.
Learn how to effectively manage pre-existing conditions like diabetes, hypertension, or thyroid disorders to minimize risks during pregnancy. This includes consulting with specialists and adjusting medication plans, empowering you for a healthy conception.
Get actionable advice on maintaining an active lifestyle during pregnancy. Learn about safe exercise routines, intensity levels, and modifications to keep you strong and healthy, benefiting both you and your baby.
Considering egg freezing? While AMH indicates egg quantity, it doesn't guarantee quality or future success. A fertility specialist explains the hard data on AMH, age, and the realities of egg freezing.
Are you anxious about future pregnancy? A specialist doctor explains the importance of "folic acid," a key element in preconception care, and its optimal intake timing.
A practical list of what is worth testing when you start thinking about pregnancy — rubella and other antibody titres, managing existing conditions, and genetic carrier screening. What to check, and when.
A guide to fertility preservation and life planning from a specialist's perspective, aiming to reduce future regrets.